Currently the main proxies are run using squid in reverse caching proxy mode.
However, have been very impressed with some of the capabilities of Apache 2.2's mod_proxy. Specifically the ability to redirect to servers based on named virtual hosts / directories etc.
I'm compiling Apache with mod_proxy as we speak.
Code:
./configure --enable-proxy --enable-proxy-httpd --enable-proxy-balancer --enable-headers --enable-file-cache --enable-cache --enable-disk-cache --enable-static-htcache-clean --prefix=/usr/local/apache --with-mpm=worker
